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ADULTS: The usual dose is one MEBAAL Plus-150 tablet once daily which can be increased as required up to 600 mg Pregabalin/day. MEBAAL Plus-150 tablet once daily can be taken with/without food. Increase dose as necessary to 1 MEBAAL Plus-150 tablet b.i.d with/without food. Dosage above 300 mg/day must be reserved only for those having on-going pain, and tolerating 300 mg Pregabalin per day. Whilst discontinuing MEBAAL Plus-150, the dose of Pregabalin must be gradually reduced over 1 week.
Dosage in Renal Dysfunction: Creatinine clearance 30-60 ml/min: 300 mg Pregabalin per day maximum dose.
Creatinine clearance 15-30 ml/min: 150 mg Pregabalin per day maximum dose.
Creatinine clearance <15 ml/min: 75 mg Pregabalin per day maximum dose.
Mode of Administration: Oral.
